Fig. 6

Schematic summary of the relative expression of transcriptional regulators during TCRαβ⁺ CD8αα⁺ IEL differentiation. Scheme shows the relative expression (normalized to 1) of Tbx21 (purple), Id2 (blue), Id3 (red), and C-myc (green) along different stages during IEL development derived from the presented qPCR and scRNA-seq data. Thymus: DP: CD4⁺CD8⁺, stage 1: CD4⁻CD8⁻TCRβ⁺NK1.1⁻CD122⁻T-bet⁻, stage 2: CD4⁻CD8⁻TCRβ⁺NK1.1⁻CD122⁺T-bet⁻, stage 3: CD4⁻CD8⁻TCRβ⁺NK1.1⁻1CD22⁺T-bet⁺