Fig. 7: Reduced microbial diversity in Il10−/− mice is restored to WT levels in Il10−/−Il22−/− mice albeit a markedly altered microbial signature. | Mucosal Immunology

Fig. 7: Reduced microbial diversity in Il10−/− mice is restored to WT levels in Il10−/−Il22−/− mice albeit a markedly altered microbial signature.

From: The development of colitis in Il10−/− mice is dependent on IL-22

Fig. 7

a Chao 1 index, b principal component analysis (unweighted, UniFrac analysis) based on 16S rRNA sequencing of DNA isolated from the feces of WT, Il10−/−, Il22−/−, and Il10−/−Il22−/− mice (10 male, 5 female per group, 12–16 weeks of age). Taxon-based analysis at c family level with d differentially expressed taxa by LEfSe analysis.

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