Fig. 5: Expression kinetics of LASI transcripts show immediate early induction with predominantly nuclear/perinuclear enrichment in HAECs. | Mucosal Immunology

Fig. 5: Expression kinetics of LASI transcripts show immediate early induction with predominantly nuclear/perinuclear enrichment in HAECs.

From: A long noncoding RNA antisense to ICAM-1 is involved in allergic asthma associated hyperreactive response of airway epithelial cells

Fig. 5

Quantification of LASI (a) and SPDEF (b) transcript levels in HAECs at 0, 0.5, 2, 6, 12, and 24 h following the treatment with 100 ng/ml LPS. Quantification of LASI (c) and SPDEF (d) transcript levels in HAECs at 0, 0.5, 2, 6, 12, and 24 h following the treatment with 10 ng/ml IL-13. Relative quantities of LASI (e) and SPDEF (f) transcripts in nuclear and cytosolic fractions of LPS and IL-13 treated HAECs compared to non-treated (NT) cells. Data shown as mean ± SEM; n = 4–6/gp; *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001, based on the one-way ANOVA and Dunnett’s multiple comparison test for (a–d), and for (e and f), compared to NT cytosolic levels based on one-way ANOVA and Tukey’s multiple comparison test.

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