Fig. 2: TSLP directly activates lymphoid cells, but not basophils, in papain-induced type 2 airway inflammation. | Mucosal Immunology

Fig. 2: TSLP directly activates lymphoid cells, but not basophils, in papain-induced type 2 airway inflammation.

From: Targeted deletion of the TSLP receptor reveals cellular mechanisms that promote type 2 airway inflammation

Fig. 2

a Representative histograms and mean fluorescence intensity (MFI) of TSLPR expression on basophils in different mouse genotypes. b Number of eosinophils and ILC2s in the BALF (n = 4). c Number of IL-5- and IL-13-positive ILC2s in the lungs (n = 4). d Representative histograms and MFI of TSLPR expression on ILC2s and CD4 + T cells in different mouse genotypes. e Number of eosinophils and ILC2s in the BALF (n = 4). f Number of IL-5- and IL-13-positive ILC2s in the lungs (n = 4). g Histology of the airways stained with PAS-alcian blue. Scale bars indicate 200 µm (low-magnification) and 100 µm (high-magnification). All data are representative of at least 2 independent experiments. NS; not significant, *P < 0.05 (Mann-Whitney U test).

Back to article page