Table 1 Bacterial burden within myeloid cell populations from Bl6 WT or Nos2−/− mice.
From: Granulocytes act as a niche for Mycobacterium tuberculosis growth
21 Days PI | 28 Days PI | % Change | |
|---|---|---|---|
Bl6 WT Ly6G high neutrophils | |||
Average bacteria per cell | 12 | 7 | −42 |
Median of the distribution | 9 | 5 | −44 |
Mode of the distribution | 5 | 2 | −60 |
Range of the distribution | 1–36 | 1–36 | ~ |
Average # infected cells per lung | 1100 | 520 | −53 |
Bl6 WT Ly6G mid granulocytes | |||
Average bacteria per cell | 5 | 4 | −20 |
Median of the distribution | 4 | 3 | −25 |
Mode of the distribution | 3 | 2 | −33 |
Range of the distribution | 1–15 | 1–15 | ~ |
Average # infected cells per lung | 900 | 350 | −61 |
Bl6 WT Ly6G Neg Mono/Macs | |||
Average bacteria per cell | 13 | 9 | −31 |
Median of the distribution | 10 | 7 | −30 |
Mode of the distribution | 4 | 3 | −25 |
Range of the distribution | 1–47 | 1–46 | ~ |
Average # infected cells per lung | 490 | 330 | −33 |
Nos2−/− Ly6G high neutrophils | |||
Average bacteria per cell | 12 | 14 | 17 |
Median of the distribution | 9 | 11 | 22 |
Mode of the distribution | 4 | 35 | 775 |
Range of the distribution | 1–35 | 1–35 | ~ |
Average # infected Cells per Lung | 700 | 4000 | 471 |
Nos2−/−Ly6G Mid granulocytes | |||
Average bacteria per cell | 5 | 6 | 20 |
Median of the distribution | 4 | 5 | 25 |
Mode of the distribution | 2 | 3 | 50 |
Range of the distribution | 1–15 | 1–15 | 0 |
Average # infected Cells per Lung | 660 | 8800 | 1233 |
Nos2−/− Ly6G Neg Mono/Macs | |||
Average bacteria per Cell | 13 | 12 | −8 |
Median of the distribution | 10 | 9 | −10 |
Mode of the distribution | 8 | 6 | −25 |
Range of the distribution | 1–47 | 1–43 | ~ |
Average # infected cells per Lung | 345 | 560 | 62 |
