Fig. 7: γδ T cells mediate protective responses to vaginal candidiasis. | Mucosal Immunology

Fig. 7: γδ T cells mediate protective responses to vaginal candidiasis.

From: γδ T cells compose a developmentally regulated intrauterine population and protect against vaginal candidiasis

Fig. 7

a C57BL/6J and Tcrd−/− females (n = 5–8) were infected intravaginally with C. albicans 529 L and fungal burden assessed 7 days post infection in vaginal lavage and uterine lysate samples. The combined vaginal and uterine fungal burden is shown. Graph indicates mean ± SD. b Neutrophil (CD11b+Ly6G+) staining in vaginal cell suspensions was analysed by flow cytometry. c Neutrophil percentage and numbers in vaginal cell suspensions (n = 4–8). Graphs indicate mean ± SEM. d Percentage and numbers of CD11b+Ly6G− cells in vaginal cell suspensions (n = 4–8). Graphs indicate mean ± SEM. Statistical significance was assessed by unpaired t-test (a) or one-way ANOVA with Sidak’s multiple comparisons post-hoc test (c, d). ns not significant *p < 0.05, **p < 0.01. Representative of five experiments.

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