Fig. 1: Sputum Xpert MTB/RIF cycle threshold (Xpert CT) values associates with other measures of Mtb Burden (time to Mtb culture positivity (TTP) and smear microscopy grade), systemic inflammation (CRP), and radiographic evidence of disease severity (Timika score). | Mucosal Immunology

Fig. 1: Sputum Xpert MTB/RIF cycle threshold (Xpert CT) values associates with other measures of Mtb Burden (time to Mtb culture positivity (TTP) and smear microscopy grade), systemic inflammation (CRP), and radiographic evidence of disease severity (Timika score).

From: Mycobacterium tuberculosis-specific CD4 T cells expressing CD153 inversely associate with bacterial load and disease severity in human tuberculosis

Fig. 1

a Correlation between Xpert CT values and time to Mtb culture positivity in HIV-uninfected (blue) and HIV-infected (red) participants. b Correlation between smear microscopy grade and Xpert CT values. Horizontal lines represent the median values. c, d Correlations between Xpert CT values and plasma C-reactive protein and Timika score on chest radiograph. The solid lines indicate the linear regression and correlations between measures were performed using a two-tailed nonparametric Spearman test.

Back to article page