Fig. 4: The proportion of CD153+ Mtb300-specific CD4 T cells inversely correlates with Mtb bacterial burden, irrespective of HIV status. | Mucosal Immunology

Fig. 4: The proportion of CD153+ Mtb300-specific CD4 T cells inversely correlates with Mtb bacterial burden, irrespective of HIV status.

From: Mycobacterium tuberculosis-specific CD4 T cells expressing CD153 inversely associate with bacterial load and disease severity in human tuberculosis

Fig. 4

a Correlation between Xpert CT values and the proportion of CD153+ Mtb300-specific CD4 T cells in HIV-uninfected (blue) and HIV-infected (red) persons. Linear regression and 95% confidence band are depicted. b Correlation between Xpert CT values and the proportion of IL-2+ Mtb300-specific CD4 T cells in HIV-uninfected and HIV-infected persons. c Correlation between the proportion of CD153+ Mtb300-specific CD4 T cells and the proportion of IL-2+ Mtb300-specific CD4 T cells in HIV-uninfected and HIV-infected persons. Correlations were tested by a two-tailed nonparametric Spearman rank test.

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