Fig. 3: Soluble factors observed in eosinophil and epithelial cell coculture. | Mucosal Immunology

Fig. 3: Soluble factors observed in eosinophil and epithelial cell coculture.

From: Bidirectional crosstalk between eosinophils and esophageal epithelial cells regulates inflammatory and remodeling processes

Fig. 3

a A 65-analyte multiplex array was used to identify inflammatory mediators in culture supernatants from 7 days of IL-5-treated eosinophil monocultures, cocultures, cocultures with IL-13, EPC2 monocultures with EPC2 monocultures with IL-13. Values within the heatmap represent the mean concentration (pg/mL) for each treatment group. b Individual analytes are plotted. Significant differences were assessed with one-way ANOVA and Tukey post-test. Bars indicate p < 0.01. Samples from three biological replicates were analyzed, with 2–3 technical replicates of each culture condition for each biological replicate. Representative data shown are mean ± SD and individual symbols represent technical replicates.

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