Fig. 6: Cigarette smoke exposure attenuates the upregulation of pIgR in the nasal mucosa following immunization. | Mucosal Immunology

Fig. 6: Cigarette smoke exposure attenuates the upregulation of pIgR in the nasal mucosa following immunization.

From: Cigarette smoke exposure attenuates the induction of antigen-specific IgA in the murine upper respiratory tract

Fig. 6

Room air (RA) and cigarette smoke (CS)-exposed mice were immunized with LPS/OVA as per Fig. 1. At 3dpb, and nasal mucosa was extracted. a Western blots for pIgR/secretory component (SC) were performed. An uncropped version of pIgR/SC blots is presented in Fig. S4. b pIgR and SC expression was quantified by densitometry. Data represent n = 5 mice per group. A.U. arbitrary units. Two-way ANOVA with Tukey’s post-hoc test. Mean ± SEM. *p < 0.05.

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