Fig. 4: Innate cytokine expression in RV-infected 6-day-old mice. | Mucosal Immunology

Fig. 4: Innate cytokine expression in RV-infected 6-day-old mice.

From: Deficient inflammasome activation permits an exaggerated asthma phenotype in rhinovirus C-infected immature mice

Fig. 4

Six-day-old C57BL/6 mice were inoculated with sham, RV-A1B, and RV-C15. Whole-lung mRNA (a) was measured using quantitative PCR, and whole-lung IL-33, IL-25, and TSLP protein (b) were examined by ELISA. (N = 7–12 from two experiments, mean ± SEM, *different from sham, †different from RV-A1B, p < 0.05, one-way ANOVA). c Two days post-infection, lungs were stained for IL-33 (red), IL-25 (green), TSLP (red), and nuclei (DAPI, black). Scale bar, 50 mm.

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