Fig. 6: Histologic changes but no change in myeloid cell recruitment in fetal lung following blocking IL-1 and TNF signaling. | Mucosal Immunology

Fig. 6: Histologic changes but no change in myeloid cell recruitment in fetal lung following blocking IL-1 and TNF signaling.

From: A potent myeloid response is rapidly activated in the lungs of premature Rhesus macaques exposed to intra-uterine inflammation

Fig. 6

a Representative 20x H&E sections of lungs from controls, LPS, LPS + IL-1RA, LPS + anti-TNF, and LPS + IL-1RA + anti-TNF exposed animals; stars denote secondary septa, arrows represent cells in alveolar space and scale bar is 100 μm. b UMAPs of the lung hematopoietic cells across treatments (n = 2-3/condition). c Percentage of myeloid (CD88+) cells within lung CD45+ cells. Each dot represents one animal. Median and interquartile ranges are displayed, Kruskai–Wallis test; **p ≤ 0.01. NS not significant.

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