Fig. 5: Expression profile of complement component genes.

a Dot plot depicting expression of genes encoding complement components C3–C9. b Violin plot showing selected cell types with differential expression of complement component genes. c Uniform Manifold Approximation and Projection (UMAP) plot illustrating differential expression of C3 and C5 in lung cells. Clusters expressing C3 are colored red, C5 colored green, clusters expressing neither are colored grey and clusters co-expressing both are colored yellow. Intensities of the colors for each gene vary from light to dark depending on the expression level (low to high). d Scatter plot showing expression of C3 and C5 across the cell types. Pearson’s correlation coefficient (R) at the top of the plot indicates the extent of correlation between the genes. Number of cells expressing the gene(s) or not expressing either gene are indicated. Data from young C57BL/6 mice (3 months old).