Fig. 5: IκBζ is required for IL-17-induced gene expression in IECs. | Mucosal Immunology

Fig. 5: IκBζ is required for IL-17-induced gene expression in IECs.

From: IκBζ controls IL-17-triggered gene expression program in intestinal epithelial cells that restricts colonization of SFB and prevents Th17-associated pathologies

Fig. 5

a Organoids were prepared from the small intestine of wild-type mice, and stimulated with IL-17A (20 ng/ml) for the indicated periods. Expression of the indicated genes was analyzed by RT-qPCR. The results are presented as the mean ± SD of triplicates and are representative of organoids from three mice. b The organoids from control (Nfkbizfl/fl) or Nfkbizfl/flVil1-Cre mice were unstimulated or stimulated with IL-17A for 24 h, and analyzed as in (a).

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