Fig. 7: Features of mucosal CD8+ T cells induced by i.n. immunization with LV::S40-HAPEHR or LV::S40-HAPEHR-20. | Mucosal Immunology

Fig. 7: Features of mucosal CD8+ T cells induced by i.n. immunization with LV::S40-HAPEHR or LV::S40-HAPEHR-20.

From: A lentiviral vector expressing a dendritic cell-targeting multimer induces mucosal anti-mycobacterial CD4+ T-cell immunity

Fig. 7

The immunized C57BL/6 mice are those studied in the Fig. 6. a Shown are lung CD8+ T cells, distinguished for their location within the interstitium (CD45i.v−) or in the vasculature (CD45i.v+). Profile of CD27 vs CD62L or CD45RB, and b CD103 vs CD69, or CD44 vs CXCR3 of the lung CD8+ T cells from the interstitium or vasculature. c Recapitulative percentages of (poly)functional CD8+ T cells specific to EsxH or EspC in the lung interstitium (top) or vasculature (bottom), as determined by ICS. Results are representative of at least two independent experiments.

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