Fig. 4: Genes modulated by IL-22 treatment at the single IEC level. | Mucosal Immunology

Fig. 4: Genes modulated by IL-22 treatment at the single IEC level.

From: Epithelial dysfunction is prevented by IL-22 treatment in a Citrobacter rodentium-induced colitis model that shares similarities with inflammatory bowel disease

Fig. 4

Heat maps of differentially expressed genes in IL-22.Fc treated mice compared to vehicle in various IEC clusters: IEC differentiation markers (a), AMPs (b), mucous layer genes (c), solute transporters (d). Clusters 0, 12 and 16 were undifferentiated cells, goblet cells and colonocytes, respectively.

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