Table 3 Mean D₂RO in Caudate & Putamen at antipsychotic oral doses as measured by displacement of [¹¹C]-raclopride

ITI-007

60 mg/day

~ 40%

Present results

Clozapine

75–900 mg/day

48–61%

Farde et al. [2]; Kapur et al. [39]; Tauscher et al. [31]

Quetiapine

150–750 mg/day

30–62%

Gefvert et al. [30]; Kapur et al. [32]; Tauscher et al. [31]; Tauscher-Wisniewski et al. [33]

Ziprasidone

40–160 mg/day

56 to >59%

Mamo et al. [43]; Vernaleken et al. [44]

Risperidone

4 mg/day

72–81%

Kapur et al. [38, 39]; Nyberg et al. [3]; Tauscher et al. [31]

Olanzapine

5–60 mg/day

61–80%

Nyberg et al. [45]; Kapur et al. [39, 46]; Tauscher et al. [31]

Lurasidone

40–80 mg

>65%

Wong et al. [5]

Cariprazine

1.5–3 mg/day

69 to >90%

Reviewed by Citrome [42]

Aripiprazole

10–30 mg

88–90%

Yokoi et al. [6]; Mamo et al. [7]