Fig. 1
From: The polygenic nature of telomere length and the anti-ageing properties of lithium
Genetic correlations with telomere length and individualised risk prediction. a Genetic correlations between single nucleotide polymorphisms predictive of increased telomere length and age-related phenotypes. b Left: Output from PRSice displaying a range of p-value thresholds (PT) tested, including the optimal PT as shown in the tallest bar at threshold PT = 0.013, which explained ~4.4% of the variance (p = 6.174 × 10−5). Right: A scatterplot showing the positive correlation between polygenic risk scores for telomere length (PRS-TL; adjusted for 3 PCs) and relative telomere length (RTL; adjusted for age, sex and BMI), Pearson (r) = 0.205, p ≤ 0.0001
