Fig. 1
From: Item-based analysis of the effects of duloxetine in depression: a patient-level post hoc study
a–c Week-by-week mean change for HDRS-17-sum (a), the depressed mood item (b) and the psychic anxiety item (c) for duloxetine- and placebo-treated subjects, respectively. Lines represent estimated means from a linear mixed model. Effect sizes at week 1, 2, 4, 6 and 8, respectively: a 0.05, 0.20, 0.27, 0.37, 0.37; b 0.20, 0.31, 0.37, 0.46, 0.44 c; 0.23, 0.29, 0.34, 0.42, 0.43. n.s. non-significant (p = 0.16); *** = p < 0.001
