Fig. 2
From: Item-based analysis of the effects of duloxetine in depression: a patient-level post hoc study

a, b Week-by-week mean change for the suicidality item for duloxetine and placebo-treated subjects, respectively, in subjects aged 25 years and above (a) subjects aged 18–24 years (b). Lines represent estimated means from a linear mixed model. Baseline scores a 0.62 points, standard deviation (SD) 0.76; b 0.53 points, SD 0.70. Effect sizes at week 1, 2, 4, 6 and 8, respectively: a 0.15, 0.23, 0.26, 0.23, 0.24; b 0.22, 0.22, 0.13, 0.25, 0.20. n.s. non-significant (p = 0.10, 0.11, 0.42, 0.16, 0.21); ***p < 0.001