Table 1 Demographic and clinical parameters for psychosis probands, their nonpsychotic relatives, and healthy controls.

From: Brain gray matter network organization in psychotic disorders

 

Probands

(N = 326)

Relatives

(N = 315)

Healthy controls

(N = 202)

F

p

 

Mean (standard deviation)

Age (years)

35.35 (12.45)

39.83 (15.68)

36.59 (12.55)

8.85

<0.001

Education

13.59 (2.41)

14.32 (2.64)

14.96 (2.39)

19.25

<0.001

GAF

53.50 (13.96)

77.08 (12.39)

86.65 (6.54)

555.03

<0.001

WRAT

100.22 (15.13)

101.25 (15.03)

103.64 (14.10)

3.36

0.035

BACS

−1.19 (1.40)

−0.32 (1.21)

0.02 (1.11)

67.69

<0.001

PANSS_Total

64.21 (17.42)

    

PANSS_Positive

16.33 (5.53)

    

PANSS_Negative

14.81 (5.44)

    

YMRS_Total

6.47 (6.27)

    

MADRS_Total

11.38 (9.33)

    

CPZ dose (mg/day)

406.31 (381.37)

    
 

N (%)

N (%)

N (%)

χ2

P

Sex (male, %)

143 (43.9%)

91 (28.9%)

88 (43.6%)

18.46

<0.001

Handed (right, %)

273 (83.7%)

272 (86.3%)

177 (87.6%)

2.48

0.648

Race

     

Caucasian

190 (58.3%)

214 (67.9%)

134 (66.3%)

12.19

0.016

African American

115 (35.3%)

86 (27.3%)

50 (24.8%)

  

Other

21 (6.4%)

15 (4.8%)

18 (8.9%)

  
  1. BACS Brief Assessment of Cognition in Schizophrenia (z-score), CPZ Chlorpromazine Equivalent Antipsychotic Dosage, GAF Global Assessment of Functioning, MADRS Montgomery-Ã…sberg Depression Rating Scale, PANSS Positive and Negative Syndrome Scale, WRAT wide-range achievement test, YMRS Young Mania Rating Scale