Table 3 Within-family correlation of network metrics that had significant intergroup differences among the participant groups.

From: Brain gray matter network organization in psychotic disorders

Regions with altered network metrics

Nodal centrality metrics

Overall probands

DSM disorders

SZ

SAD

BD

Network metrics altered in psychotic probands

 STG, L

Efficiency

r = 0.25, P = 0.009

/

/

/

 STP, L

Efficiency

/

/

/

/

 STP, R

Efficiency

/

/

/

/

 MTG, L

Efficiency

/

/

/

/

Network metrics altered in nonpsychotic relatives

 MFG, R

Degree

/

/

/

/

 IFG_Orb, R

Degree

/

/

/

/

 PCG, L

Degree

/

/

/

/

 Hippocampus, L

Degree

/

/

/

/

 Pallidum, L

Degree

/

/

/

/

 Thalamus, L

Degree

r = 0.39, P < 0.001

/

r = 0.55, P =0.002

/

 MFG, R

Efficiency

/

/

/

/

 IFG_Orb, R

Efficiency

/

/

/

/

 PCG, L

Efficiency

/

/

/

/

 Hippocampus, L

Efficiency

r = 0.23, P = 0.018

/

/

/

 Thalamus, L

Efficiency

r = 0.41, P < 0.001

r = 0.44, P = 0.017

r = 0.58, P = 0.001

/

  1. BD psychotic bipolar I disorder, FDR false discovery rate, SAD schizoaffective disorder, SZ schizophrenia, MFG middle frontal gyrus, MTG middle temporal gyrus, IFG_Orb orbital inferior frontal gyrus, PCG posterior cingulate gyrus, STG superior temporal gyrus, STP superior temporal pole, L left, R right
  2. *P-values listed in the table were corrected using FDR