Fig. 1: Overview of study design. | Neuropsychopharmacology

Fig. 1: Overview of study design.

From: Brain micro-architecture and disinhibition: a latent phenotyping study across 33 impulsive and compulsive behaviours

Fig. 1

Disinhibition scores for each subject were extracted using a previously validated optimal bi-factor model. We first (Part A) used Partial Least Squares (PLS) regression to map intra-cortical myelination to those disinhibition scores. We then (Part B) used PLS to identify genes inferentially over-expressed in those disinhibition-related brain regions.

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