Fig. 2: Cue-induced regional activations and functional connectivity.
From: Noradrenergic correlates of chronic cocaine craving: neuromelanin and functional brain imaging
A One-sample t test of drug vs. neutral cues in CU. Voxels showing higher activation during drug vs. neutral and neutral vs. drug are shown in warm and cool colors, respectively. Voxel p < 0.001, uncorrected. Clusters that met cluster p < 0.05, FWE-corrected are listed in Table 2. B (upper panel) Cue-induced functional connectivity (gPPI) with bilateral PHG in CU: one-sample t test of drug vs. neutral cues. Voxels showing higher gPPI during drug vs. neutral are shown in warm colors. Voxel p < 0.001, uncorrected. Clusters that met cluster p < 0.05, FWE-corrected are listed in Supplementary Table S1. No clusters showed higher gPPI in response to neutral vs. drug cues. B (lower panel) LC and VTA/SNc masks and linear regression of LC and VTA/SNc gPPI with PHG vs. CCQ scores in CU.
