Table 2 Cue-induced activations: one-sample t test of drug vs. neutral in CU.

Regions	Cluster	Voxel	MNI coordinates (mm)
	Size (voxels)	Z value	X	Y	Z
Activation: drug > neutral cue*
L inferior occipital G	905	Inf	−42	−76	−2
R inferior temporal G	634	7.45	45	−61	−8
R supramarginal G	537	7.18	42	−37	40
L superior parietal lobule	788	7.18	−39	−46	55
Middle cingulate cortex	88	6.38	3	2	31
L precentral G	211	6.03	−48	2	34
L cerebellum	109	5.91	−21	−73	−50
R cerebellum	202	5.87	12	−76	−44
L superior frontal G	173	5.73	−18	47	43
R precentral G	157	5.64	51	11	25
Ventromedial PFC	58	5.61	0	35	−23
L anterior insula	30	5.47	−36	−4	7
L amygdala	51	5.16	−33	−10	−23
L thalamus	12	5.04	−3	−31	4
L caudate	24	4.99	−27	35	−14
Activation: drug < neutral cue
L parahippocampal G	115	−6.62	−27	−46	−8
R parahippocampal G	118	−5.76	27	−43	−8

An asterisk indicates clusters surviving peak voxel p < 0.05 FWE corrected, with the cluster size shown for voxels meeting this threshold; L and R parahippocampal clusters also showed a peak voxel Z value that met voxel p < 0.05 FWE corrected; however, the cluster sizes are shown for voxel p < 0.001, uncorrected—thus, these clusters correspond exactly in size to those shown in Fig. 2A.
L left, R right, G gyrus, PFC prefrontal cortex.

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