Table 1 (a) SMR and (b) S-TissueXcan gene sets associated with cognitive function. Only novel results are displayed.
From: Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics
Gene sets | Gene Set P | Gene set categories |
|---|---|---|
(a) SMR | ||
GOBP:regulation_of_binding | 8.54E−06 | Cell binding |
REACTOME:Signaling_by_Rho_GTPases | 2.28E−06 | Cell metabolism |
GOBP:small_GTPase_mediated_signal_transduction | 2.13E−05 | Cell metabolism |
REACTOME:Signaling_by_Rho_GTPases | 3.05E−07 | Cell metabolism |
GOBP:nucleosome_organization | 5.92E−06 | Cell structure |
GOBP:protein-DNA_complex_assembly | 1.81E−06 | Cell structure |
GOBP:protein-DNA_complex_subunit_organization | 2.17E−07 | Cell structure |
GOBP:cell-substrate_adhesion | 5.06E−06 | Cell structure |
GOBP:response_to_glucose | 4.80E−06 | Interaction with small molecules |
GOBP:response_to_hexose | 3.73E−06 | Interaction with small molecules |
GOBP:response_to_monosaccharide | 8.65E−06 | Interaction with small molecules |
GOBP:macromolecule_methylation | 4.62E−08 | Methylation |
GOBP:methylation | 3.29E−07 | Methylation |
REACTOME:Ion_channel_transport | 1.00E−05 | Neuronal/Dendritic regulation/development |
(b) S-TissueXcan | ||
GOMF:actin_binding | 6.44E−06 | Cell binding |
GOMF:chromatin_binding | 4.52E−06 | Cell binding |
GOBP:cellular_macromolecular_complex_assembly | 1.71E−07 | Cell structure |
GOBP:cellular_protein_complex_assembly | 1.68E−07 | Cell structure |
GOBP:cellular_response_to_interferon-gamma | 2.67E−06 | Interaction with small molecules |
