Table 2 Results of the analyses of the occurrence rate and entry rate of the CAPs for bilateral and unilateral left amygdala seeds.
From: Dynamics of amygdala connectivity in bipolar disorders: a longitudinal study across mood states
SEED | Mixed model | Main effect of Mood | β estimates (SE) | P value | ||
|---|---|---|---|---|---|---|
Euthymia (E) | Depression (D) | Hypomania (H) | ||||
BILAT. | INT-CAP | |||||
Occurrence rate | F = 4.1, p = 0.021 | 17.7 (2.4) | 17.9 (3.3) | 27.3 (3.2) | H > E, p = 0.009 H > D, p = 0.027 | |
Entry rate | F = 4.7, p = 0.012 | 19.0 (2.3) | 17.1 (3.0) | 27.1 (2.9) | H > E, p = 0.011 H > D, p = 0.008 | |
LEFT | DMN-CAP | |||||
Occurrence rate | F = 3.2, p = 0.048 | 14.3 (2.0) | 22.8 (2.9) | 14.2 (2.9) | D > E, p = 0.020 D > H, p = 0.043 | |
Entry rate | F = 4.6, p = 0.014 | 14.0 (1.7) | 22.7 (2.5) | 13.8 (2.5) | D > E, p = 0.006 D > H, p = 0.015 | |
SEED | Regression in the patients | β estimates (SE) | t | p | ||
BILAT. | INT-CAP | |||||
Occurrence rate | YMRS | Global mania | 0.73 (0.29) | 2.54 | 0.014 | |
Y1 | Irritable mania | 2.81 (0.98) | 2.87 | 0.006 | ||
Y2 | Elated maniaa | 2.33 (1.11) | 2.11 | 0.039 | ||
Entry rate | YMRS | Global mania | 0.65 (0.26) | 2.56 | 0.013 | |
Y1 | Irritable mania | 2.4 (0.87) | 2.78 | 0.007 | ||
Y2 | Elated maniaa | 2.05 (0.98) | 2.10 | 0.040 | ||
LEFT | DMN-CAP | |||||
Occurrence rate | MADRS | Global depression | 0.82 (0.25) | 3.29 | 0.002 | |
M1 | Sadness | 3.45 (1.01) | 3.41 | 0.001 | ||
M2 | Negative thoughts | 2.74 (0.74) | 3.69 | 0.0004 | ||
M3 | Detachment | 2.57 (0.81) | 3.16 | 0.002 | ||
Entry rate | MADRS | Global depression | 0.77 (0.22) | 3.56 | 0.0007 | |
M1 | Sadness | 3.30 (0.88) | 3.77 | 0.0003 | ||
M2 | Negative thoughts | 2.46 (0.65) | 3.79 | 0.0003 | ||
M3 | Detachment | 2.23 (0.71) | 3.31 | 0.001 | ||
M4a | Neurovegetative symptoms | 2.27 (1.04) | 2.18 | 0.032 | ||
