Fig. 2: Cluster characterization in the discovery sample with variables used in the clustering pipeline.

A horizontal line represents the mean, and the error bars indicate the standard deviation, whereas the dot size is proportional to the number of individuals with the given value. Variables that were significant in the one-vs-all comparisons are marked with an asterisk sign. A Hamilton Depression Rating Scale (HAMD, 21 items, clinician-administered), range 0–66, scores >7 indicate (mild) depression. B Hamilton Anxiety Rating Scale (HAMA), range 0–56, scores >17 indicate mild to moderate anxiety severity. C Scale for the Assessment of Negative Symptoms (SANS, sum score), range 0–80, a higher score indicates more severe negative symptoms. For subscales, see Table S3. D Scale for the Assessment of Positive Symptoms (SAPS, sum score), range 0–86, a higher score indicates more severe positive symptoms. For subscales, see Table S3. E Beck Depression Inventory (BDI-II, self-reported), range 0–63, scores >9 indicate (mild) depression. F Symptom Checklist–Global Severity Index, an index of overall psychological distress, range 0–4, higher scores reflect higher levels of psychopathological distress as well as a greater severity of self-reported symptoms. G Childhood Trauma Questionnaire sum score, range 25–125, a higher score indicates more experiences of childhood trauma. H SF36–Quality of life measurements–Mental health, range 0–100, high scores define a more favorable health state.