Fig. 3: Prolonged cortisol reactivity effects on white matter tracts versus white matter tract findings in the ENIGMA studya.
From: White matter in prolonged glucocorticoid response to psychological stress in schizophrenia
Response to stressor tasks measured with salivary cortisol at the immediate, acute, and prolonged reactivity timepoints in HC (A–C) and SSD (D–F). aENIGMA = Enhancing Neuro Imaging Genetics Through Meta-Analysis. Effect sizes of the 23 major white matter regions in the ENIGMA study are used, with higher values indicating more severe impairment in SSD patients compared with HC subjects in the ENIGMA meta-analysis (x-axis). Correlation coefficients between fractional anisotropy (FA) of each region and psychological stressor task measure in the present study are shown (y-axis).
