Table 1 Participant demographic and clinical information.

From: White matter in prolonged glucocorticoid response to psychological stress in schizophrenia

 

HC (n = 117)

SSD (n = 121)

Test statistic

p value

Age [years] (SD)

35.4 (13.6)

36.6 (13.3)

t = −0.73

0.47

Sex (% male)

52%

69%

χ2 = 7.78

<0.01

Current smoker (%)

32.5%

43.8%

χ2 = 3.23

0.048

BPRSa (SD)

23.7 (4.2)

38.9 (10.7)

t = −14.20

3 × 10−33

BNSSb (SD)

2.4 (5.7)

16.1 (14.4)

t = −9.48

4 × 10−18

Processing speedc

78.0 (16.5)

60.3 (19.9)

t = 7.29

5 × 10−12

Working memoryd

20.5 (4.3)

17.4 (5.4)

t = 4.79

3 × 10−6

CPZ (SD)e

NA

495.5 (462.7)

NA

NA

Average Motion Distance per Frame (SD)

1.05 (0.53)

1.42 (1.32)

t = −2.72

0.007

  1. aBrief Psychiatric Rating Scale (BPRS) calculation based on data from n = 116 SSD patients and 116 HC.
  2. bBrief Negative Symptom Scale (BNSS) calculation based on data from n = 111 SSD patients and 116 HC.
  3. cDigit Symbol Test for processing speed calculation based on data from n = 112 SSD patients and 115 HC.
  4. dDigit Sequence Test for working memory calculation based on data from n = 113 SSD patients and 115 HC.
  5. eAntipsychotic medication dose is provided in chlorpromazine equivalent dose (CPZ) (milligrams per day).
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