Fig. 4: Subjective assessments of sleep measured by visual analogue scales in the Subjective Quality of Sleep Questionnaire (SQSQ) following the baseline and three treatment nights.

White bars indicate baseline, black bars indicate placebo, hatched bars indicate 20 mg and grey bars indicate 50 mg. Significant differences between placebo and JNJ-48816274 treatment are indicated by *p < 0.05 and **p < 0.01.