Fig. 3: Network GBC changes to speed of dopamine increases and individual differences in subjective ‘high’ to methylphenidate.
From: Brain connectivity changes to fast versus slow dopamine increases
In exploratory testing, the hippocampus (and no other network) showed a significant correlation between GBC patterns to fast dopamine increases and ‘high’ ratings. The x-axis is the area under the curve (AUC) representing an aggregate measure of the total ‘high’ reported across the scanning session. The y-axis shows beta values for each participant demonstrating the association between fast dopamine increases and GBC. Note: in the oral session only 13 out of 20 participants reported feeling any ‘high’, so there may be floor effects for this session.
