Fig. 1: Elevated in vivo [11C]PBR28 SUVR in female adults with ASD compared to age- and TSPO genotype-matched CON. | Neuropsychopharmacology

Fig. 1: Elevated in vivo [11C]PBR28 SUVR in female adults with ASD compared to age- and TSPO genotype-matched CON.

From: In vivo translocator protein in females with autism spectrum disorder: a pilot study

Fig. 1

Group mean [11C]PBR28 SUVR maps of females with ASD (top) and female CON (middle). Statistical map from voxelwise comparison of [11C]PBR28 SUVR between groups, controlled for age and TSPO genotype, shows elevated regional TSPO levels relative to whole brain mean in the midcingulate cortex and splenium of the corpus callosum in ASD (N = 12) compared to CON (N = 10) (Z > 2.3, pcluster < 0.05) (bottom). TSPO translocator protein, ASD autism spectrum disorder, CON control, SUVR standardized uptake value ratio, N number.

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