Table 2 Group platelet serotonin concentrations: Median (IQR).

From: Fetal behavior and gestational serotonin reuptake inhibitor exposure: relationships between behavior, drug dosage, plasma drug level, and a measure of drug bioeffect

 

GROUPS

GROUP COMPARISONS

 

ND (n = 29)

DEP (n = 17)

DEP&ND combined (n = 46)

DEP + SRI (n = 17)

ND v. DEP p-value

DEP&ND v. DEP + SRI p-value

 

Mean (Range)

  

Maternal Platelet 5-HT (ng/mL)

133 (107–166)

165 (112–203)

141 (108–180)

17.0 (10.1–27.2)

0.39

<0.001

Maternal Platelet 5-HT (ng/billion)

657 (590–884)

796 (548–942)

719 (576–901)

97.0 (52.2–179)

0.76

<0.001

Infant Platelet 5-HT (ng/mL)

75.0 (52.6–92.9)

83.3 (50.1–113)

78.8 (50.7–97.9)

21.0 (14.7–34.2)

0.50

<0.001

Infant Platelet 5-HT (ng/billion)

391 (265–532)

328 (245–497)

383 (240–527)

109 (65.7–138)

0.40

<0.001

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