Fig. 2: Mice treated with THC during adolescence show an elevation in drug-induced reinstatement of morphine-seeking behaviors later in life. | Neuropsychopharmacology

Fig. 2: Mice treated with THC during adolescence show an elevation in drug-induced reinstatement of morphine-seeking behaviors later in life.

From: Neural basis of adolescent THC-induced potentiation of opioid responses later in life

Fig. 2

A Time spent in the morphine-paired chamber during CPP pre-test, post-test, extinction, and reinstatement. Mice treated with THC or vehicle during adolescence showed a similar trajectory of CPP and extinction. B Quantification of the time spent in the morphine-paired chamber in the reinstatement task relative to the final extinction day. Vehicle/morphine-treated mice 660 s vs 732 s, p = 0.33, n = 10; THC/morphine-treated mice 781 s vs. 1015 s, p = 0.015, n = 8.

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