Fig. 4: Adolescent THC exposure changes input connectivity to VTADA cells.
From: Neural basis of adolescent THC-induced potentiation of opioid responses later in life
A Schematic of experiments. B Representative image of the ventral midbrain of a DAT-Cre mouse showing starter cells in the VTA and medial SNc. Scale, 1 mm. C Representative images of input cell populations in several brain sites, including the anterior cortex, NAcMed, NAcCore, NAcLat, MHb, LHb, and PBN. Scale, 250 μm. D Bar graph plot showing the percentage of RABV-labeled inputs in control vs. THC-treated mice. Two-way ANOVA, interaction p = 0.0062. Only the anterior cortex was significantly different following correction for multiple comparisons (corrected p-value p = 0.029).
