Table 3 Significant and suggestive lead SNPs from the cross-ancestry GWAS meta-analysis of the Million Veteran Program and Indivior cohorts.
From: Multi-ancestry genome-wide association meta-analysis of buprenorphine treatment response
Chromosome | Position | SNP | P value | Nearest Gene |
---|---|---|---|---|
2 | 196279963 | rs149319538 | 2.66 × 10–08 | AC064834.1 |
11 | 114180814 | rs2852445 | 6.60 × 10–07 | NNMT |
6 | 122683440 | rs9401519 | 7.36 × 10–07 | RNU1-18P |
6 | 54294688 | rs669917 | 1.55 × 10–06 | CLNS1AP1 |
8 | 130043829 | rs6470688 | 1.70 × 10–06 | LINC00977 |
6 | 54695917 | rs12215138 | 2.22 × 10–06 | RP11-524H19.2 |
9 | 71905345 | rs147697343 | 2.37 × 10–06 | FAM189A2 |
6 | 54365478 | rs573501000 | 4.16 × 10–06 | CLNS1AP1 |
13 | 111459167 | rs72663484 | 4.23 × 10–06 | LINC00567 |
13 | 102667059 | rs60776232 | 5.00 × 10–06 | FGF14 |
2 | 153461929 | rs66706786 | 5.21 × 10–06 | FMNL2 |
1 | 2563901 | rs147506475 | 6.47 × 10–06 | MMEL1 |
10 | 14767985 | rs113072550 | 6.50 × 10–06 | FAM107B |
17 | 29691368 | rs2057769 | 7.72 × 10–06 | NF1 |
16 | 83173960 | rs9932942 | 9.50 × 10–06 | CDH13 |
4 | 179359799 | rs72706653 | 9.81 × 10–06 | RNA5SP173 |