Fig. 4: Drug-Seq transcriptomic results for secondary screen.

A Number of differentially expressed genes (DEG) resulting from the comparison of all replicates of a given compound vs. select DMSO replicates (see Supplementary Methods). Active RNA compounds had more DEG than 95% of the DMSO vs. DMSO comparisons. B UMAP of active RNA compounds shows grouping of replicates.