Table 2 Relationship between [11C]CURB λk3 and symptom measures in MDD group.

From: Fatty acid amide hydrolase in major depressive episodes: A [11C]CURB positron emission tomography study

Depressive Severity

Hamilton Depression Rating Scalea

All Prioritized Regionsb

mPFC

dlPFC

OFC

ACC

HPC

 

F1,11 < 0.01 p = 0.97

r = −0.10

r = −0.22

r = 0.10

r = 0.30

r = −0.18

p = 0.75

p = 0.47

p = 0.74

p = 0.32

p = 0.56

Apathy

Marin Apathy Evaluation Scalea

All Prioritized Regionsb

mPFC

OFC

ACC

Substantia Nigra

Midbrainc

Ventral Striatum

 

F1,11 = 6.81 p = 0.02*

r = 0.67

r = 0.64

r = 0.33

r = 0.70

r = 0.51

r = 0.60

p = 0.01*

p = 0.02*

p = 0.27

p = 0.01*

p = 0.08

p = 0.03*

Anxiety

Hamilton Anxiety Rating Scalea

All Prioritized Regionsb

OFC

ACC

HPC

Amygdala

Insula

 

F1,11 = 0.75 p = 0.49

r = −0.13

r = −0.15

r = −0.13

r = 0.02

r = −0.05

p = 0.67

p = 0.63

p = 0.68

p = 0.94

p = 0.86

  1. mPFC medial prefrontal cortex, dlPFC dorsolateral prefrontal cortex, OFC orbitofrontal cortex, ACC anterior cingulate cortex, HPC hippocampus.
  2. aPartial Pearson Correlation Coefficient.
  3. bMixed effects model analysis.
  4. cMidbrain ROI not including the substantia nigra.
  5. *p < 0.05 (p-values uncorrected).
Back to article page