Table 2 Cognitive outcome measures.
CBD | Placebo | CBD vs. Placebo | |||||
|---|---|---|---|---|---|---|---|
Screening visit | Post-cannabis | Post-cannabis | Mean difference | P value | Corrected P value | ||
HVLT-R | Immediate recall | 19.3 (17.2 to 21.4) | 14.7 (12.8 to 16.7) | 16.6 (14.6 to 18.5) | −1.8 (−3.5 to −0.2) | 0.04 | 0.14 |
Immediate intrusions | 0.9 (0.6 to 1.2) | 2.1 (0.9 to 3.2) | 1.9 (0.8 to 3.1) | 0.1 (−0.8 to 1.0) | 0.80 | 0.80 | |
Immediate repetitions | 1.3 (0.7 to 2.0) | 1.2 (0.4 to 2.0) | 1.7 (0.9 to 2.5) | −0.5 (−1.4 to 0.4) | 0.29 | 0.40 | |
Delayed recall | 5.2 (4.4 to 6.1) | 3.5 (2.5 to 4.5) | 4.8 (3.8 to 5.9) | −1.3 (−2.0 to −0.6) | 0.001 | NA | |
Delayed intrusions | 0.5 (0.2 to 0.8) | 0.8 (0.1 to 1.5) | 1.1 (0.4 to 1.8) | −0.3 (−1 to 0.3) | 0.3 | 0.40 | |
Delayed repetitions | 0.2 (0.0 to 0.3) | 0.2 (−0.1 to 0.5) | 0.4 (0.1 to 0.7) | −0.2 (−0.5 to 0.0) | 0.07 | 0.19 | |
Digit Span | Forward | 5.9 (5.6 to 6.3) | 5.9 (5.5 to 6.4) | 6.2 (5.7 to 6.7) | −0.3 (−0.6 to 0.1) | 0.12 | 0.25 |
Reverse | 3.9 (3.6 to 4.3) | 3.7 (3.3 to 4.2) | 3.7 (3.2 to 4.1) | 0.1 (−0.4 to 0.6) | 0.74 | 0.80 |
