Fig. 3: IGF1 promotes food intake in wild-type mice
From: Central IGF1 improves glucose tolerance and insulin sensitivity in mice
IGF1 or an anti-IGF1 antibody were injected ICV (2 ul, 1 ug/ml). AAV-Igf1 was injected into the ARC (1011 GC/mouse) of wild-type mice. a & b Food consumption 48 h after IGF1 and anti-IGF1 injection, n = 10 per group. c & d Body weight 48 h after IGF1 and anti-IGF1 injection, n = 10 per group. (e & f) Food consumption and body weight 2 weeks after virus injection, n = 12 per group. Data are expressed as means ± SD. *P < 0.05, **P < 0.01 vs. saline or AAV-GFP group
