Table 3 Secondary endpoints according to BMI categories at baseline

From: Associations between body mass index and the risk of renal events in patients with type 2 diabetes

 

Microalbuminuria (n)

Microalbuminuria vs. not

Macroalbuminuria (n)

Macroalbuminuria vs. not

Doubling of creatinine, ESRD or renal death (n)

Doubling of creatinine, ESRD or renal death vs. not

 

No

Yes

HR

p for trend

No

Yes

HR

p for trend

No

Yes

HR

p for trend

 

(95% CI)

(95% CI)

(95% CI)

Normal weight

2102

792

Ref.

0.01

2779

115

Ref.

0.02

2851

43

Ref.

0.09

Overweight

3229

1111

0.99

  

0.91

  

0.84

(0.90–1.09)

4198

142

(0.70–1.18)

4290

50

(0.54–1.28)

Obesity grade 1

1719

546

1.03

2188

77

1.08

2240

25

0.94

(0.92–1.17)

(0.78–1.49)

(0.55–1.62)

Obesity grade 2

536

208

1.28

712

32

1.37

731

13

1.55

(1.08–1.51)

(0.89–2.12)

(0.78–3.08)

Obesity grade 3

221

73

1.19

276

18

2.18

287

7

2.57

(0.93–1.53)

(1.27–3.73)

(1.08–6.15)

  1. Hazard ratios computed by Cox proportional hazards regression analyses adjusted as in model 1: baseline age, sex, region of origin, prior cardiovascular disease, estimated glomerular filtration rate (and its square), urinary albumin to creatinine ratio, history of ever smoking, and study allocations.