Table 1 Summary of GPAT family enzymes
From: Update on glycerol-3-phosphate acyltransferases: the roles in the development of insulin resistance
Gene | Other symbol | Molecular mass | Reaction to NEM | Subcellular localization | Tissue distribution | Ref. | |
|---|---|---|---|---|---|---|---|
GPAT1 | / | 94 kDa | Resistant | Mitochondria | BAT > WAT > liver > muscle > brain | ||
GPAT2 | / | 88 kDa (human)89 kDa (mice) | Sensitive | Mitochondria | Testis > liver > adipose tissue | ||
GPAT3 | AGPAT8/AGPAT10 | 50 kDa | Sensitive | Endoplasmic reticulum | Adipose tissue > small intestine > heart > brain > liver | ||
GPAT4 | AGPAT6 | 52 kDa | Sensitive | Endoplasmic reticulum | BAT, testis > liver, kidney, brain, intestine, WAT | ||
