Fig. 1: The effect of sex hormone and dietary consumption on LV function at different time courses (4, 8, and 12 weeks).

A The LV function at 4 weeks. B The LV function at 8 weeks. C The LV function at 12 weeks. *P < 0.05 vs sex-matched ND-Sham (n = 6/group). †P < 0.05 vs male orchiectomized rats (n = 6/group). ‡P < 0.05 vs female high-fat diet-fed ovariectomized rats (n = 6/group). S sham, ND normal diet, HFD high-fat diet, ORX orchiectomized rats, OVX ovariectomized rats.