Fig. 4: The effect of sex hormone and dietary consumption on cardiac mitochondrial membrane depolarization at different time courses (4, 8, and 12 weeks).

A The cardiac mitochondrial membrane depolarization at 4 weeks. B The cardiac mitochondrial membrane depolarization at 8 weeks. C The cardiac mitochondrial membrane depolarization at 12 weeks. *P < 0.05 vs sex-matched ND-Sham (n = 6/group). †P < 0.05 vs male orchiectomized rats (n = 6/group). S sham, ND normal diet, HFD high-fat diet, ORX orchiectomized rats, OVX ovariectomized rats.