Table 2 Outcomes Absolute Values and Multivariate Cox regression analysis.

From: No obesity paradox in patients with community-acquired pneumonia – secondary analysis of a randomized controlled trial

 

Underweight (BMI < 18.5)

Normal weight (BMI 18.5–25)

Overweight (BMI 25–30)

Obese (BMI > 30)

Multivariable adjusted regression analysis OR, HR or regression coefficient (95% CI)

Underweight vs. Normal weight

Overweight vs. Normal weight

Obese vs. Normal weight

Primary outcome

OR/HR

P value

OR/HR

P value

OR/HR

P value

§TTCS (days)

4.4 (3.0–6.8)

3.4 (3.0–4.0)

3.0 (2.6–4.0)

4.4 (3.5–5.0)

#0.63

0.008

#1.01

0.88

#0.82

0.07

Secondary outcomes

LOS (days)

7.0 (7.0–11.0)

7.0 (6.0–7.0)

7.0 (6.0–7.0)

7.0 (6.0–8.0)

#0.55

<0.001

#1.00

0.96

#0.97

0.79

30-day Mortality

4 (8.7)

10 (3.5)

6 (2.2)

7 (4.1)

2.19

0.28

0.58

0.35

1.41

0.58

ICU admission

0

15 (5.3)

10 (3.7)

11 (6.5)

0.72

0.47

1.04

0.93

ƒCAP complications

18 (39.1)

71 (27.3)

80 (31.5)

50 (31.9)

1.71

0.13

1.19

0.40

1.19

0.46

Intravenous antibiotics (days)

5.0 (3.0–8.0)

4.0 (3.0–6.0)

5.0 (3.0–6.5)

4.0 (3.0–6.0)

+1.47

0.049

+0.19

0.63

+−0.05

0.91

Total antibiotics (days)

10.0 (7.5–14.0)

8.0 (7.0–11.0)

9.0 (7.0-11.0)

9.0 (7.0–11.0)

+2.54

0.003

+−0.05

0.91

+0.05

0.93

  1. Data are presented as n, n (%) or median (interquartile range), ICU intensive care unit, TTCS time to clinical stability, LOS length of hospital stay, CAP community-acquired pneumonia. #hazard ratio; ¶odds ratio; +regression coefficient; §TTCS defined as time to clinical stabilization of vital signs at two consecutive measurements 12 h apart ƒ: CAP complications defined as recurrence, acute respiratory distress syndrome, empyema, nosocomial infections until day 30, or serious adverse events possibly related to CAP, ICU stay or readmission to hospital.