Fig. 5 | Nutrition & Diabetes

Fig. 5

From: Palmitoylated prolactin-releasing peptide treatment had neuroprotective but not anti-obesity effect in fa/fa rats with leptin signaling disturbances

Fig. 5

Synaptogenesis and neuroimflammation in brain. Synaptophysin and syntaxin 1A as a marker of synaptogenesis (A) and neuronal marker NeuN (B) in hippocampi detected by western blot. Marker of neurogenesis doublecortin in hippocampi (C) detected immunohistochemically. Marker of neuroinflammation GFAP detected by western blot (D) and representative photomicrograph of neuroinflammatory markers GFAP and Iba1 (E) at the end of experiment in control saline and fa/fa saline. Data are presented as means ± SEM. Statistical analysis was performed by One-way ANOVA. Significance is *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001 (n = 7–8).

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