Table 1 Clinical data of low-zinc and normal-zinc groups.

From: Influence of zinc levels and Nrf2 expression in the clinical and pathological changes in patients with diabetic nephropathy

 

Normal zinc (n = 14)

Low zinc (n = 16)

P-value

Male (n, %)

10 (71.4%)

4 (25.0%)

0.026*

Age

48.3 ± 13.8

45.3 ± 11.8

0.530

History of diabetes (years)

7.9 ± 6.4

10.3 ± 7.8

0.384

BMI

27.0 ± 4.1

23.5 ± 4.1

0.033*

SBP (mmHg)

135.0 (130.0,162.5)

140.0 (130.5,157.5)

0.785

DBP (mmHg)

83.1 ± 7.7

90.0 ± 10.2

0.045*

RBC (*109)

4.6 ± 0.8

3.5 ± 0.5

<0.001*

Hb (g/L)

140.5 (116.8,153.5)

105.0 (101.0,116.8)

0.001*

Plt (*1011)

254.5 (209.1,292.5)

265.5 (194.1,309.2)

0.901

Alb (g/L)

34.9 (24.5,45.9)

27.6 (24.1,33.4)

0.146

TG (mmol/L)

1.8 (1.4,2.6)

1.9 (1.4,2.3)

0.835

TC (mmol/L)

5.7 ± 1.7

6.6 ± 1.8

0.154

HbA1c (mg/dl)

7.0 (6.4,8.2)

7.3 (5.9,8.1)

0.917

UA(μmol/L)

385.3 ± 67.1

340.3 ± 81.1

0.113

Scr (μmol/L)

111.4 ± 43.8

125.3 ± 50.6

0.432

BUN (mmol/L)

7.1 (6.0,11.3)

8.3 (6.7,11.2)

0.618

eGFR [mL/(min.1.73 m2)]

70.4 ± 30.6

57.6 ± 30.3

0.259

24-h urinary protein (g)

5.0 ± 3.9

6.2 ± 2.9

0.333

  1. Sex of the two groups was compared by the chi-square test. Age, history of diabetes, BMI, DBP, RBC, TC, UA, Scr, eGFR, and 24-h urinary protein of the two groups were compared by t-test. SBP, the level of Hb, Plt, Alb, TC, HbA1c, BUN, copper, and zinc/copper of the two groups were compared by the Wilcoxon rank-sum test.
  2. BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, Hb hemoglobin, Alb plasma albumin, TC total cholesterol, TG triglyceride, HbA1c glycated hemoglobin, UA uric acid, Scr serum creatinine, BUN blood urea nitrogen, eGFR estimated glomerular filtration rate.
  3. *P < 0.05.
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