Table 3 Mediation effects of dietary sodium on NAFLD with CRP and red cell distribution width as mediators.
Without adjustment for β-carotene | With adjustment for β-carotene | |||||
---|---|---|---|---|---|---|
Estimatesa | 95% CIs | P-values | Estimatesb | 95% CIs | P-values | |
HSI-defined NAFLD | ||||||
CRP | ||||||
Total effect | 0.0662 | 0.0497–0.0862 | <0.0001 | 0.0683 | 0.0492–0.0844 | <0.0001 |
Direct effect | 0.0605 | 0.0402–0.0788 | <0.0001 | 0.0633 | 0.0432–0.0775 | <0.0001 |
Indirect effect | 0.0057 | 0.0021–0.0091 | <0.0001 | 0.0050 | 0.0021–0.0083 | <0.0001 |
Red cell distribution width | ||||||
Total effect | 0.0675 | 0.0483–0.0883 | <0.0001 | 0.0676 | 0.0534–0.0826 | <0.0001 |
Direct effect | 0.0663 | 0.0478–0.0869 | <0.0001 | 0.0665 | 0.0529–0.0819 | <0.0001 |
Indirect effect | 0.0012 | 0.0002–0.0027 | <0.0001 | 0.0011 | 0.0002–0.0022 | 0.0400 |
FLI-defined NAFLD | ||||||
CRP | ||||||
Total effect | 0.0686 | 0.0374–0.1010 | <0.0001 | 0.0752 | 0.0481–0.1072 | <0.0001 |
Direct effect | 0.0605 | 0.0322–0.0918 | <0.0001 | 0.0680 | 0.0402–0.0992 | <0.0001 |
Indirect effect | 0.0081 | 0.0024–0.0162 | <0.0001 | 0.0072 | 0.0009–0.0121 | <0.0001 |
Red cell distribution width | ||||||
Total effect | 0.0701 | 0.0383–0.0981 | <0.0001 | 0.0747 | 0.0501–0.1072 | <0.0001 |
Direct effect | 0.0692 | 0.0384–0.0967 | <0.0001 | 0.0739 | 0.0490–0.1071 | <0.0001 |
Indirect effect | 0.0009 | −0.0001 to 0.0027 | 0.0800 | 0.0008 | −0.0004 to 0.0019 | 0.2000 |