Table 5 Hazard ratios of incident diabetes per 1 ng/ml higher total plasma 25-hydroxyvitamin D according to vitamin-D binding protein genotype (rs7041 and rs4588).
From: The association of serum vitamin D with incident diabetes in an African American population
Interaction models | rs4588 (n = 1910) | ||
|---|---|---|---|
AA/AC HR (95% CI) | CC HR (95% CI) | P for interaction | |
No. of events/N | 57/388 | 274/1522 | |
Unadjusted | 0.99 (0.95, 1.03) | 0.98 (0.96, 1.00) | 0.649 |
Model 1 | 0.98 (0.94, 1.02) | 0.97 (0.95, 0.99) | 0.617 |
Model 2 | 0.98 (0.94, 1.02) | 0.97 (0.95, 0.99) | 0.767 |
Model 3 | 0.98 (0.94, 1.02) | 0.98 (0.96, 1.00) | 0.975 |
Interaction models | rs7041 (n = 1894) | ||
GG/GT HR (95% CI) | TT HR (95% CI) | P for interaction | |
No. of events/N | 114/556 | 217/1338 | |
Unadjusted | 0.98 (0.95, 1.01) | 0.98 (0.96, 1.00) | 0.925 |
Model 1 | 0.97 (0.94, 1.00) | 0.97 (0.95, 0.99) | 0.997 |
Model 2 | 0.97 (0.94, 1.00) | 0.97 (0.95, 0.99) | 0.980 |
Model 3 | 0.98 (0.95, 1.01) | 0.98 (0.96, 1.01) | 0.664 |
